Publications (19 of 26 listed)

 

 

 

1:

Sensitive and specific identification of wild type and variant proteins from 8 to 669 kDa using top-down mass spectrometry.

Karabacak NM, Li L, Tiwari A, Hayward LJ, Hong P, Easterling ML, Agar JN.

Mol Cell Proteomics. 2009 Apr;8(4):846-56. Epub 2008 Dec 15.

PMID: 19074999 [PubMed - in process]

2:

A hierarchical algorithm for calculating the isotopic fine structures of molecules.

Li L, Kresh JA, Karabacak NM, Cobb JS, Agar JN, Hong P.

J Am Soc Mass Spectrom. 2008 Dec;19(12):1867-74. Epub 2008 Aug 15.

PMID: 18818092 [PubMed - indexed for MEDLINE]

3:

Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival.

Wang Q, Johnson JL, Agar NY, Agar JN.

PLoS Biol. 2008 Jul 29;6(7):e170.

PMID: 18666828 [PubMed - indexed for MEDLINE]

4:

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis.

Kabashi E, Agar JN, Hong Y, Taylor DM, Minotti S, Figlewicz DA, Durham HD.

J Neurochem. 2008 Apr 1. [Epub ahead of print]

PMID: 18315558 [PubMed - as supplied by publisher]

5:

Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth.

Morris AM, Watzky MA, Agar JN, Finke RG.

Biochemistry. 2008 Feb 26;47(8):2413-27. Epub 2008 Feb 5. Review.

PMID: 18247636 [PubMed - indexed for MEDLINE]

6:

Matrix solution fixation: histology-compatible tissue preparation for MALDI mass spectrometry imaging.

Agar NY, Yang HW, Carroll RS, Black PM, Agar JN.

Anal Chem. 2007 Oct 1;79(19):7416-23. Epub 2007 Sep 7.

PMID: 17822313 [PubMed - indexed for MEDLINE]

7:

Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis.

Taylor DM, Gibbs BF, Kabashi E, Minotti S, Durham HD, Agar JN.

J Biol Chem. 2007 Jun 1;282(22):16329-35. Epub 2007 Mar 27.

PMID: 17389599 [PubMed - indexed for MEDLINE]

8:

NifS-mediated assembly of [4Fe-4S] clusters in the N- and C-terminal domains of the NifU scaffold protein.

Smith AD, Jameson GN, Dos Santos PC, Agar JN, Naik S, Krebs C, Frazzon J, Dean DR, Huynh BH, Johnson MK.

Biochemistry. 2005 Oct 4;44(39):12955-69.

PMID: 16185064 [PubMed - indexed for MEDLINE]

9:

Proteasome activity or expression is not altered by activation of the heat shock transcription factor Hsf1 in cultured fibroblasts or myoblasts.

Taylor DM, Kabashi E, Agar JN, Minotti S, Durham HD.

Cell Stress Chaperones. 2005 Autumn;10(3):230-41.

PMID: 16184768 [PubMed - indexed for MEDLINE]

10:

Overexpression of metallothionein protects cultured motor neurons against oxidative stress, but not mutant Cu/Zn-superoxide dismutase toxicity.

Taylor DM, Minotti S, Agar JN, Durham HD.

Neurotoxicology. 2004 Sep;25(5):779-92.

PMID: 15288509 [PubMed - indexed for MEDLINE]

11:

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis.

Kabashi E, Agar JN, Taylor DM, Minotti S, Durham HD.

J Neurochem. 2004 Jun;89(6):1325-35.

PMID: 15189335 [PubMed - indexed for MEDLINE]

12:

Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency.

Antonicka H, Leary SC, Guercin GH, Agar JN, Horvath R, Kennaway NG, Harding CO, Jaksch M, Shoubridge EA.

Hum Mol Genet. 2003 Oct 15;12(20):2693-702. Epub 2003 Aug 19.

PMID: 12928484 [PubMed - indexed for MEDLINE]

13:

IscA, an alternate scaffold for Fe-S cluster biosynthesis.

Krebs C, Agar JN, Smith AD, Frazzon J, Dean DR, Huynh BH, Johnson MK.

Biochemistry. 2001 Nov 20;40(46):14069-80.

PMID: 11705400 [PubMed - indexed for MEDLINE]

14:

Sulfur transfer from IscS to IscU: the first step in iron-sulfur cluster biosynthesis.

Smith AD, Agar JN, Johnson KA, Frazzon J, Amster IJ, Dean DR, Johnson MK.

J Am Chem Soc. 2001 Nov 7;123(44):11103-4. No abstract available.

PMID: 11686732 [PubMed - indexed for MEDLINE]

15:

Characterization of the NifU and NifS Fe-S cluster formation proteins essential for viability in Helicobacter pylori.

Olson JW, Agar JN, Johnson MK, Maier RJ.

Biochemistry. 2000 Dec 26;39(51):16213-9.

PMID: 11123951 [PubMed - indexed for MEDLINE]

16:

IscU as a scaffold for iron-sulfur cluster biosynthesis: sequential assembly of [2Fe-2S] and [4Fe-4S] clusters in IscU.

Agar JN, Krebs C, Frazzon J, Huynh BH, Dean DR, Johnson MK.

Biochemistry. 2000 Jul 11;39(27):7856-62.

PMID: 10891064 [PubMed - indexed for MEDLINE]

17:

Modular organization and identification of a mononuclear iron-binding site within the NifU protein.

Agar JN, Yuvaniyama P, Jack RF, Cash VL, Smith AD, Dean DR, Johnson MK.

J Biol Inorg Chem. 2000 Apr;5(2):167-77.

PMID: 10819462 [PubMed - indexed for MEDLINE]

18:

NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein.

Yuvaniyama P, Agar JN, Cash VL, Johnson MK, Dean DR.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):599-604.

PMID: 10639125 [PubMed - indexed for MEDLINE]

19:

The Azotobacter vinelandii NifEN complex contains two identical [4Fe-4S] clusters.

Goodwin PJ, Agar JN, Roll JT, Roberts GP, Johnson MK, Dean DR.

Biochemistry. 1998 Jul 21;37(29):10420-8.

PMID: 9671511 [PubMed - indexed for MEDLINE]